02214nas a2200265 4500008004100000022001400041245018400055210006900239260001500308300001000323490000800333520136200341653001401703653003201717653001501749653002501764100001501789700001901804700001901823700001601842700001201858700001601870700001501886856004701901 2020 eng d a1313-298900aThe complete mitochondrial genome sequence of Scolopendra mutilans L. Koch, 1878 (Scolopendromorpha, Scolopendridae), with a comparative analysis of other centipede genomes0 acomplete mitochondrial genome sequence of iScolopendra mutilansi c08/04/2020 a73-880 v9253 a

Scolopendra mutilans L. Koch, 1878 is an important Chinese animal with thousands of years of medicinal history. However, the genomic information of this species is limited, which hinders its further application. Here, the complete mitochondrial genome (mitogenome) of S. mutilans was sequenced and assembled by next-generation sequencing. The genome is 15,011 bp in length, consisting of 13 protein-coding genes (PCGs), 14 tRNA genes, and two rRNA genes. Most PCGs start with the ATN initiation codon, and all PCGs have the conventional stop codons TAA and TAG. The S. mutilans mitogenome revealed nine simple sequence repeats (SSRs), and an obviously lower GC content compared with other seven centipede mitogenomes previously sequenced. After analysis of homologous regions between the eight centipede mitogenomes, the S. mutilans mitogenome further showed clear genomic rearrangements. The phylogenetic analysis of eight centipedes using 13 conserved PCG genes was finally performed. The phylogenetic reconstructions showed Scutigeromorpha as a separate group, and Scolopendromorpha in a sister-group relationship with Lithobiomorpha and Geophilomorpha. Collectively, the S. mutilans mitogenome provided new genomic resources, which will improve its medicinal research and applications in the future.

10aChilopoda10aChinese medicinal materials10amitogenome10aScolopendra mutilans1 aHu, Chaoyi1 aWang, Shuaibin1 aHuang, Bisheng1 aLiu, Hegang1 aXu, Lei1 aHu, Zhigang1 aLiu, Yifei uhttps://zookeys.pensoft.net/article/47820/